Metabolic Theory of Cancer

The Warburg Theory

Otto Warburg was one of the greatest scientists of the 20th century. He won the Nobel Prize in Physiology or Medicine in 1931 for his discovery of the nature and mode of action of the respiratory enzyme.

The Otto Warburg Cancer Theory or hypothesis was that cancer growth is caused by tumor cells generating energy mainly by anaerobic breakdown of glucose. This is in contrast to healthy cells, which mainly generate energy from the oxidative breakdown of pyruvate. In short, according to Warburg, cancer should be interpreted as a mitochondrial dysfunction.

Warburg stated, cancer, above all other diseases, has countless secondary causes. But, even for cancer, there is only one prime cause. Summarized in a few words, the prime cause of cancer is the replacement of the respiration of oxygen in normal body cells by a fermentation of sugar.

Leading Researchers and Physicians in This Field:

  • Dr Thomas Seyfried - Professor at Boston College, Dr. Seyfried is one of the world's leading cancer researchers
  • Dr. Nasha Winters - Doctor of Naturopathy & Naturopathic Oncology
  • Dr. Dominic D'Agostino - Associate Professor, College of Medicine Molecular Pharmacology & Physiology Research Scientist, Inst. Human and Machine Cognition